Energy Partitioning Research Articles

Energy partitioning over an irrigated vineyard in arid northwest China: Variation characteristics, influence degree, and path of influencing factors

In this study, a two-year experiment in an irrigated vineyard was conducted to investigate the variations in energy fluxes (net radiation, Rn; latent heat flux, LE; sensible heat flux, H; and soil heat flux, G) and quantify the influence of arid advection and environmental factors (vapor pressure deficit (VPD), Rn, air temperature, wind speed, precipitation, and volumetric soil water content) on energy partitioning in arid Northwest China. For the diurnal variation, the peak values of the energy fluxes appeared at approximately 14:00, except for G (which appeared at approximately 16:00). LE was the main consumer of daytime (Rn>0) energy during the growing season (average LE/(Rn–G) was 87% and 89% in the two years), even during the shooting and leaf-fall stages. Arid advection, which affects energy partitioning mainly by increasing atmospheric evaporative demand and providing heat energy, contributed 6–60% and 1–56% of the average daytime LE during the two growing seasons, especially at the fruiting stage. Moreover, advection accounted for more than half of average daytime energy imbalances. We found that the arid advection induced by irrigation could be attenuated by selecting a reasonable irrigation time. According to the structural equation modeling (SEM) analysis, Rn had the strongest direct and positive regulation effect on LE at the half-hourly and daily scales, indicating that LE was limited by energy rather than water in the study area. The influence of Rn on LE gradually weakened with an increase in the time scale, whereas the effect of VPD increased, which may have been due to the smaller time-lag effect between VPD and LE. The diurnal variations in LE at approximately 08:00–19:30 and 19:30–08:00 were mainly controlled by the direct positive effects of Rn and VPD, respectively. The results obtained in this study will provide a better understanding of surface processes and help improve water resource management in arid agricultural areas.

Energy partition in underwater nanosecond laser ablation

Energy partition in underwater nanosecond laser ablation

Decoupling of nitrogen allocation and energy partitioning in rice after flowering.

Estimation of energy partitioning at leaf scale, such as fluorescence yield (ΦF) and photochemical yield (ΦP), is crucial to tracking vegetation gross primary productivity (GPP) at global scale. Nitrogen is an important participant in the process of light capture, electron transfer, and carboxylation in vegetation photosynthesis. However, the quantitative relationship between leaf nitrogen allocation and leaf energy partitioning remains unexplored. Here, a field experiment was established to explore growth stage variations in energy partitioning and nitrogen allocation at leaf scale using active fluorescence detection and photosynthetic gas exchange method in rice in the subtropical region of China. We observed a strongly positive correlation between the investment proportion of leaf nitrogen in photosynthetic system and ΦF during the vegetative growth stage. There were significant differences in leaf energy partitioning, leaf nitrogen allocation, and the relationship between ΦF and ΦP before and after flowering. Furthermore, flowering weakened the correlation between the investment proportion of leaf nitrogen in photosynthetic system and ΦF. These findings highlight the crucial role of phenological factors in exploring seasonal photosynthetic dynamics and carbon fixation of ecosystems.

Quantified Plasma Heating and Energy Dissipation in the Earth’s Quasi-perpendicular Bow Shock

The high-speed solar wind decelerates as it travels through the Earth’s bow shock, during which a portion of the incident flow energy is converted into the plasma thermal energy. However, the energy partition of plasma heating among different species, as well as the energy dissipation mechanism, remains elusive. In this paper, we quantify the plasma heating and the energy dissipation by calculating the pressure–strain interactions in 33 quasi-perpendicular bow shocks observed by the Magnetospheric Multiscale spacecraft. Our results show that the Joule dissipation measured by J·E′ and the quasi-viscous dissipation quantified by PiD are distinct in the examined shocks. We also reveal that ions gain more energy than electrons, and the compressive effect is more important than the incompressible channel in plasma heating. PiD contributed by the gyrotropic pressure tensor is consistently positive for electrons; however, there is no discernible distinction between the gyrotropic and nongyrotropic contribution to PiD for ions.

Relative Yield of Thermal and Nonthermal Emission during Weak Flares Observed by STIX during 2021 September 20–25

The disparate nature of the thermal–nonthermal energy partition during flares, particularly during weak flares, is still an open issue. Following the Neupert effect, quantifying the relative yield of X-ray emission in different energy bands can enable the inferring of the underlying energy release mechanism. During 2021 September 20–25, the Solar Orbiter mission—being closer to the Sun (∼0.6 au) and having a moderate separation angle (<40°) from the Sun–Earth line—offered a unique opportunity to analyze multiwavelength emission from ∼200 (mostly weak) flares, commonly observed by the Spectrometer Telescope for Imaging X-rays (STIX), STEREO-A, GOES, and the Solar Dynamics Observatory. Associating the quotient (q f ) of hard X-ray fluence (12–20 keV) and soft X-ray flux (4–10 keV) with the peak soft X-ray flux enabled us to identify strongly nonthermal flares. A multiwavelength investigation of spectral and imaging-mode observations of the 20 strongly nonthermal weak flares reveals an inverse relationship of q f with the emission measure (and density), and a positive relationship with the flare plasma temperature. This indicates that the plasma in tenuous loops attains higher temperatures compared to that in the denser loops, in response to nonthermal energy deposition. This is in agreement with the plasma parameters of the coronal loops, as derived by applying the one-dimensional Palermo–Harvard hydrodynamical code to coronal loop plasma with different initial coronal loop base pressures when subjected to similar heating inputs. Our investigation, therefore, indicates that the plasma parameters of the flaring loop in the initial phase have a decisive role in the thermal–nonthermal energy partitioning.

Electron and Proton Energization in 3D Reconnecting Current Sheets in Semirelativistic Plasma with Guide Magnetic Field

Using 3D particle-in-cell simulation, we characterize energy conversion, as a function of guide magnetic field, in a thin current sheet in semirelativistic plasma, with relativistic electrons and subrelativistic protons. There, magnetic reconnection, the drift-kink instability (DKI), and the flux-rope kink instability all compete and interact in their nonlinear stages to convert magnetic energy to plasma energy. We compare fully 3D simulations with 2D in two different planes to isolate reconnection and DKI effects. In zero guide field, these processes yield distinct energy conversion signatures: ions gain more energy than electrons in 2Dxy (reconnection), while the opposite is true in 2Dyz (DKI), and the 3D result falls in between. The flux-rope instability, which occurs only in 3D, allows more magnetic energy to be released than in 2D, but the rate of energy conversion in 3D tends to be lower. Increasing the guide magnetic field strongly suppresses DKI, and in all cases slows and reduces the overall amount of energy conversion; it also favors electron energization through a process by which energy is first stored in the motional electric field of flux ropes before energizing particles. Understanding the evolution of the energy partition thus provides insight into the role of various plasma processes, and is important for modeling radiation from astrophysical sources such as accreting black holes and their jets.

Reflection of plane waves in a rotating micropolar double porous thermoelastic medium with temperature dependent properties

AbstractThe objective of this empirical investigation is to explore the behavior of different waves reflected in a homogenous isotropic double porous structured micropolar thermoelastic medium with rotation and temperature‐dependent characteristics. Three‐phase‐lag theory of thermoelasticity is adopted to acquire the governing equations of the model. Six coupled plane waves have been found to propagate across the medium at distinct velocities. Derivation for energy and amplitude ratios of reflected waves were carried out by employing appropriate boundary conditions. For different angles of incidence, the outcomes for energy partition were determined numerically and displayed graphically. It is found that amplitude ratios associated with various reflected waves are affected by angular velocity, temperature‐dependent properties, micropolar parameter, and double porosity. Also, it has been discovered that throughout the reflection phenomena there is no dissipation of energy. Furthermore, this study concludes with a summary of the findings and subsequent observations. The current investigation has yielded inferences regarding specific cases that are of particular interest.

Photosystem II Tolerance to Excess Zinc Exposure and High Light Stress in Salvia sclarea L.

High light (HL) intensity has a substantial impact on light energy flow and partitioning within photosynthetic apparatus. To realize the impact of HL intensity on zinc (Zn) tolerance mechanisms in clary sage (Salvia sclarea L., Lamiaceae) plants, we examined the effect of the altered chlorophyll and nutrient uptake under excess Zn supply on the response mechanism of photosystem II (PSII) photochemistry. Eight-week-old clary sage plants were treated with 5 μM Zn (control) or 900 μM Zn in Hoagland nutrient solution. Leaf elemental analysis for Zn, Mn, Mg, and Fe was performed by inductively coupled plasma mass spectrometry (ICP-MS), whereas PSII functioning under HL was evaluated by chlorophyll fluorescence imaging analysis. Exposure of S. sclarea plants to 900 μM Zn increased leaf Zn accumulation and decreased leaf Mg and chlorophyll. The decreased non-photochemical quenching (NPQ) provided evidence of the photoprotection offered by the smaller light-harvesting antennae due to the reduced chlorophyll. The increased Mn after Zn exposure corresponded with higher efficiency of the oxygen-evolving complex (OEC) that was significantly correlated with the maximum efficiency of photosystem II (PSII) photochemistry (Fv/Fm). An increased electron transport rate (ETR) coincided with increased leaf Fe, which is known to play a vital role in the enzymes engaged in ETR. The decreased (32%) NPQ after an 8-day exposure to Zn caused an increased (10%) quantum yield of non-regulated energy loss in PSII (ΦNO), indicative of an increased singlet oxygen (1O2) production. It is suggested that the decreased NPQ induced acclimation responses of clary sage plants to HL and excess Zn by increasing 1O2 production. The reduced (18%) excess excitation energy (EXC) at PSII and the increased (24%) quantum yield of PSII photochemistry (ΦPSII) and ETR indicated improved photosynthetic efficiency under excess Zn and HL intensity. Therefore, the exposure of medicinal plants to excess Zn not only boosts their photosynthetic efficiency, enhancing crop yields, but can also improve Fe and Zn content, ameliorating the human health deficiency of these two essential micronutrients.

149 Using respiratory gas flux and backward dietary energy partitioning to estimate energy intake by beef cattle fed a high concentrate diet

Abstract Twelve Charolais steers (BW = 498 ± 47.4 kg) were used in a 73-d feeding experiment. Our objective was to determine if CH4 and CO2 emissions, and O2 consumption could be used as biomarkers to estimate energy intake in growing beef cattle when integrated with backward dietary energy partitioning calculations when fed a high concentrate diet. Steers were housed in a pen equipped with individual feed bunks with access to an automated head chamber system (AHCS; GreenFeed, C-Lock, Inc., Rapid City, SD). Steers were randomly assigned to 1 of 3 treatments according to DMI as multiple of maintenance, which are 1.1 (1.1 M, n = 4), 1.4 (1.4 M, n = 4), and 1.8 (1.8 M, n = 4). The diet fed was 35% chopped sorghum hay (CP = 6.39% of DM; in vitro OM digestibility = 57.77%) and 65% concentrate (CP = 19.10% of DM; in vitro OM digestibility = 91.84%). The concentrate consisted of 41.75% flaked corn, 8.5% cottonseed meal, 13% distillers’ grain and 1.75% limestone. Steers were supplemented daily with 0.85 kg of alfalfa pellets (Medicago sativa; CP= 16.55%; in vitro OM digestibility = 87.01%) that were fed through the AHCS as bait. Methane tended (P = 0.09) and CO2 emissions and O2 consumption (P &amp;lt; 0.01) increased with the increasing feeding rates. Measured gross energy (GE; 21.9, 24.8, 29.5 Mcal/d, respectively), digestible energy (DE; 19.7, 22.0, 25.8 Mcal/d, respectively), and metabolizable energy (ME; 17.2, 19.2, 22.7 Mcal/d, respectively) intake levels increased with the increases in energy retention and heat production. The predicted values for GE (17.4, 23.6, 28.2 Mcal/d), DE (15.1, 20.8, 24.4 Mcal/d), and ME (12.6, 17.9, 21.3 Mcal/d) intake rates increased with the increase from 1.1 M to 1.8 M. Comparison of measured and predicted GE, DE, and ME intake rates agreed closely (r = 0.95, 0.93, 0.92 Pearson correlation, respectively). This experiment shows that together with multiple short-term breath measurements from an AHCS, BW, and an estimate of average daily gain, GE, DE, and ME intakes by cattle consuming a high concentrate diet can be predicted.

Spring Irrigation Reduces the Frequency and Intensity of Summer Extreme Heat Events in the North China Plain

AbstractIrrigation has distinct impacts on extreme temperatures. Due to the carryover effect of soil moisture into other seasons, temperature impacts of irrigation are not limited to irrigated seasons. Focusing on the North China Plain, where irrigation occurs in both spring (March‐April‐May) and summer (June‐July‐August), with a higher proportion of irrigation water applied during spring, we investigate the impact of spring irrigation on summer extreme heat events. Based on partial correlation analysis of data products, we find positive correlations between spring and summer soil moisture, suggesting that spring irrigation‐induced water surplus persists into the following summer and affects regional climate by impacting surface energy partitioning. Regional climate simulations confirm cross‐seasonal climatic effects and show that spring irrigation reduces the frequency and intensity of summer extreme heat events by approximately −2.5 days and −0.29°C, respectively. Our results highlight the importance of the cross‐seasonal climatic effect of irrigation in mitigating climate extremes.

A Mini-Review of the Kinetic Energy Partition Method in Quantum Mechanics

Based on the idea of adiabatic symmetry, we present a novel basis set expansion method—the kinetic energy partition (KEP) method—for solving quantum eigenvalue problems. Broken symmetry is responsible for quantum entanglement in many-body systems via parametric non-adiabatic corrections. Starting from simple one-particle-in-one-dimension problems, we gradually increase the complexity in the number of particles and the interaction patterns. Our goal in the mini-review is to advocate for the utility of the KEP method in front-line research, in particular for research beginners in quantum many-body problems.

On-fault earthquake energy density partitioning from shocked garnet in an exhumed seismic midcrustal fault.

The energy released during an earthquake is mostly dissipated in the fault zone and subordinately as radiated seismic waves. The on-fault energy budget is partitioned into frictional heat, generation of new grain surface by microfracturing, and crystal-lattice distortion associated with dislocation defects. The relative contribution of these components is debated and difficult to assess, but this energy partitioning strongly influences earthquake mechanics. We use high-resolution scanning-electron-microscopy techniques, especially to analyze shocked garnet in a fault wall-rock, to provide the first estimate of all three energy components for a seismic fault patch exhumed from midcrustal conditions. Fault single-jerk seismicity is recorded by the presence of pristine quenched frictional melt. The estimated value of energy per unit fault surface is ~13 megajoules per square meter for heat, which is predominant with respect to both surface energy (up to 0.29 megajoules per square meter) and energy associated with crystal lattice distortion (0.02 megajoules per square meter).

Probing Non-Covalent Interactions through Molecular Balances: A REG-IQA Study.

The interaction energies of two series of molecular balances (1-X with X = H, Me, OMe, NMe2 and 2-Y with Y = H, CN, NO2, OMe, NMe2) designed to probe carbonyl…carbonyl interactions were analysed at the B3LYP/6-311++G(d,p)-D3 level of theory using the energy partitioning method of Interacting Quantum Atoms/Fragments (IQA/IQF). The partitioned energies are analysed by the Relative Energy Gradient (REG) method, which calculates the correlation between these energies and the total energy of a system, thereby explaining the role atoms have in the energetic behaviour of the total system. The traditional "back-of-the-envelope" open and closed conformations of molecular balances do not correspond to those of the lowest energy. Hence, more care needs to be taken when considering which geometries to use for comparison with the experiment. The REG-IQA method shows that the 1-H and 1-OMe balances behave differently to the 1-Me and 1-NMe2 balances because the latter show more prominent electrostatics between carbonyl groups and undergoes a larger dihedral rotation due to the bulkiness of the functional groups. For the 2-Y balance, REG-IQA shows the same behaviour across the series as the 1-H and 1-OMe balances. From an atomistic point of view, the formation of the closed conformer is favoured by polarisation and charge-transfer effects on the amide bond across all balances and is counterbalanced by a de-pyramidalisation of the amide nitrogen. Moreover, focusing on the oxygen of the amide carbonyl and the α-carbon of the remaining carbonyl group, electrostatics have a major role in the formation of the closed conformer, which goes against the well-known n-π* interaction orbital overlap concept. However, REG-IQF shows that exchange-correlation energies overtake electrostatics for all the 2-Y balances when working with fragments around the carbonyl groups, while they act on par with electrostatics for the 1-OMe and 1-NMe2. REG-IQF also shows that exchange-correlation energies in the 2-Y balance are correlated to the inductive electron-donating and -withdrawing trends on aromatic groups. We demonstrate that methods such as REG-IQA/IQF can help with the fine-tuning of molecular balances prior to the experiment and that the energies that govern the probed interactions are highly dependent on the atoms and functional groups involved.

Robust land surface temperature record for north China over the past 21,000 years.

Numerous proxy reconstructions have provided general insight into late Quaternary East Asian Monsoon variability. However, challenges persist in precisely assessing absolute temperature impacts on proxy variations. Here, we use two independent paleothermometers, based on bacterial membrane lipids and clumped isotopes of snail shells, in the same section of the western Chinese Loess Plateau to establish a robust land surface temperature record spanning the past approximately 21,000 years. Our independent temperature records consistently reveal (i) similar land surface temperatures between the Last Glacial Maximum and late Holocene and (ii) a gradual cooling Holocene, which contrasts with the climate model predictions. We propose that changes in soil moisture availability over the deglaciation modulates the land surface temperature recorded by the proxies. A land surface energy partitioning model confirms this mechanism, suggesting that effects of soil moisture availability should be properly considered when comparing proxy records with climate model outputs.

Use of Increasing Levels of Low-Quality Forage in Dairy Cows’ Diets to Regulate Enteric Methane Production in Subtropical Regions

Dairy cows are the highest daily and annual methane (CH4) producers among all cattle categories. So, the present study aimed to evaluate the effect of increasing supplementation levels of a low-quality forage on dry matter intake (DMI), DM digestibility (DMD), milk production, enteric CH4 emission, gross energy, and protein partitioning in Holstein cows. In total, eight cows (112 ± 38 days postpartum; mean ± s.d.) were randomly assigned to 4 treatments composed of 4 dietary neutral detergent fibre (NDF) inclusion levels (40.2% (control), 43.3%, 46.5%, and 50.5%) in a 4 × 4 repeated Latin square experimental design. The cows were fed corn + alfalfa silage and a concentrate (60:40 forage:concentrate ratio). To increase the contents of low-quality NDF, part of the silage was replaced with maize stover (MSTV). The CH4 production was measured in an open-circuit respiration chamber. The DMI increased significantly and linearly (p &lt; 0.05) with increasing levels of MSTV. However, the CH4 yield decreased (p &lt; 0.0001) as the NDF level increased (32.1, 28.1, 23.1, and 21.3 CH4 L/kg DMI, respectively). DMD decreased as NDF levels in the diet increased (p &lt; 0.0001). The NDF digestibility (DNDF) explained the better (p &lt; 0.0001) CH4 production response than DMD. It was concluded that low-quality forages can be used to regulate CH4 production in subtropical and tropical climate regions.

Photosynthetic Responses of Racomitrium japonicum L. to Strontium Stress Evaluated through Chlorophyll a Fluorescence OJIP Transient Analysis.

Nuclides pollution and its biological effects are of great concern, especially for bryophytes during their terrestrial adaptation. Understanding PSII activity and electron transport response is vital for comprehending moss abiotic stress reactions. However, little is known about the photosynthetic performance of moss under nuclide treatment. Therefore, this study aimed to evaluate the chlorophyll fluorescence of Racomitrium japonicum L. The moss was subjected to Sr2+ solutions at concentrations of 5, 50, and 500 mg/L to evaluate chlorophyll a fluorescence using the OJIP test. Moderate and high Sr2+ stress led to inner cell membrane dissolution and reduced chlorophyll content, indicating impaired light energy absorption. At 5 mg/L Sr2+, fluorescence kinetics showed increased light energy capture, energy dissipation, and total photosynthetic driving force, thus stimulating transient photosynthetic activity of PSII and improving PSI reduction. Linear electron transfer and PSII stability significantly decreased under moderate and high Sr2+ stress, indicating potential photosynthetic center damage. Cyclic electron transfer (CEF) alleviated photosynthetic stress at 5 mg/L Sr2+. Thus, low Sr2+ levels stimulated CEF, adjusting energy flux and partitioning to protect the photosynthetic apparatus. Nevertheless, significant damage occurred due to inefficient protection under high Sr2+ stress.

A molecular electron density theory study of hydrogen bond catalysed polar Diels–Alder reactions of α,β-unsaturated carbonyl compounds

The hydrogen bond (HB) catalysed Diels-Alder (DA) reactions of acrolein with cyclopentadiene have been investigated within the Molecular Electron Density Theory (MEDT) at the ωB97X-D/6-311G(d,p) computational level. The formation of HBs increases the electrophilicity of these species, suggesting an acceleration of these polar Diels-Alder (P-DA) reactions with forward electron density flux. Formation of one or two HBs with acrolein decreases the activation energies of the HB-catalysed P-DA reactions by 1.7 (methanol) and 4.0 (squaramide) kcal·mol−1, with the corresponding DA reactions exhibiting low endo stereoselectivity. These HB-catalysed DA reactions proceed through non-concerted one-step mechanisms via asynchronous transition state structures (TSs). An Interacting Quantum Atoms (IQA) energy partitioning analysis of the TSs indicates that the intra-atomic stabilization of the acrolein framework, coupled with the increase of the global electron density transfer, plays a crucial role in reducing the activation energies of these HB-catalysed DA reactions.

Fluid-injection control on energy partitioning during the earthquake cycle

During an earthquake, the elastic energy stored in the Earth is released as frictional energy and radiated energy in the form of seismic waves. The partitioning of energy released during an earthquake gives an indication of the overall size of the earthquake and its potential for damage to man-made structures. Here, we perform an energy analysis of fluid-injection-induced earthquakes using a single-degree-of-freedom spring poroslider and rate-and-state friction. We show that seismic radiation can be modeled within the single-degree-of-freedom spring-slider by adding a radiation damping term. We then use it to study fluid injection and assess its effects on the energy partitioning during induced and triggered earthquakes. We find that: (1) seismic efficiency, stress drop, and total slip are directly influenced by the rate of increase in pore pressure, (2) the ratio of elastic energy stored in the skeleton to injection energy is low and is influenced by the rate of fluid injection, (3) seismic injection efficiency is also low and is lower for induced earthquakes compared to triggered ones, and (4) fluid injection leads to bigger and potentially more damaging earthquakes overall.

Energy partition between submesoscale internal waves and quasi-geostrophic vortical motion in the pycnocline

Abstract Shipboard ADCP velocity and towed CTD chain density measurements from the eastern North Pacific pycnocline are used to segregate energy between linear internal waves (IW) and linear vortical motion (quasi-geostrophy, QG) in 2-D wavenumber space spanning submesoscale horizontal wavelengths λx ∼ 1 – 50 km and finescale vertical wavelengths λz ∼ 7 – 100 m. Helmholtz decomposition and a new Burger-number Bu decomposition yield similar results despite different methodologies. Partition between IW and QG total energies depends on 𝐵𝑢. For Bu &lt; 0.01, available potential energy EP exceeds horizontal kinetic energy EK and is contributed mostly by QG. In contrast, energy is nearly equipartitioned between QG and IW for Bu » 1. For Bu &lt; 2, EK is contributed mainly by IW, and EP by QG, while, for Bu &gt; 2, contributions are reversed. Vertical shear variance is contributed primarily by near-inertial IW at small λz, implying negligible QG contribution to vertical shear instability. Conversely, both QG and IW at the smallest λx ∼ 1 km contribute large horizontal shear variance, such that both may lead to horizontal shear instability. Both QG and IW contribute to vortex-stretching at small vertical scales. For QG, the relative vorticity contribution to linear potential vorticity anomaly increases with decreasing horizontal and increasing vertical scales.

The Metabolic Syndrome, a Human Disease.

This review focuses on the question of metabolic syndrome (MS) being a complex, but essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of related but rather independent pathologies. The human nature of MS (its exceptionality in Nature and its close interdependence with human action and evolution) is presented and discussed. The text also describes the close interdependence of its components, with special emphasis on the description of their interrelations (including their syndromic development and recruitment), as well as their consequences upon energy handling and partition. The main theories on MS's origin and development are presented in relation to hepatic steatosis, type 2 diabetes, and obesity, but encompass most of the MS components described so far. The differential effects of sex and its biological consequences are considered under the light of human social needs and evolution, which are also directly related to MS epidemiology, severity, and relations with senescence. The triggering and maintenance factors of MS are discussed, with especial emphasis on inflammation, a complex process affecting different levels of organization and which is a critical element for MS development. Inflammation is also related to the operation of connective tissue (including the adipose organ) and the widely studied and acknowledged influence of diet. The role of diet composition, including the transcendence of the anaplerotic maintenance of the Krebs cycle from dietary amino acid supply (and its timing), is developed in the context of testosterone and β-estradiol control of the insulin-glycaemia hepatic core system of carbohydrate-triacylglycerol energy handling. The high probability of MS acting as a unique complex biological control system (essentially monophyletic) is presented, together with additional perspectives/considerations on the treatment of this 'very' human disease.